What effect do corticosteroids have on body fat distribution?

Corticosteroids are known to have a significant impact on body fat distribution, primarily by redistributing fat rather than reducing or normalizing it. When corticosteroids are used, they can lead to a phenomenon known as "Cushingoid" changes, where fat is redistributed to specific areas of the body, such as the abdomen, face, and back of the neck.

This redistribution occurs due to various mechanisms, including the effect corticosteroids have on metabolism and appetite. Instead of promoting a healthy balance of fat throughout the body's typical distribution patterns, corticosteroids can lead to an increase in abdominal or visceral fat, which is associated with various metabolic complications. Therefore, the characterization of corticosteroids' effect on body fat distribution as a process of redistribution closely aligns with observed clinical outcomes in individuals undergoing corticosteroid therapy.