What is commonly affected in hematopoietic cells due to chemotherapy treatment?

Prepare for the APHON Principles of Chemotherapy and Biotherapy Test. Engage with flashcards and multiple choice questions. Enhance your knowledge and get ready for certification!

Chemotherapy treatments are designed to target rapidly dividing cells, which include not only cancer cells but also healthy cells in the bone marrow, leading to significant effects on hematopoietic cells that are responsible for blood cell production.

When these cells are affected, multiple systems within the body can experience disruptions:

  • Reduced oxygen transport occurs because chemotherapy can lead to a decrease in red blood cell production, resulting in anemia. Anemia diminishes the blood's ability to carry oxygen effectively, which can lead to fatigue and other symptoms related to insufficient oxygen supply to tissues.

  • Decreased blood clotting ability is a consequence of reduced levels of platelets, known as thrombocytes. Chemotherapy can impair platelet production in the bone marrow, which increases the risk of bleeding and bruising due to the inadequate clotting mechanism.

  • Increased infectious disease susceptibility arises from the reduction in white blood cells, particularly neutrophils, which are critical for fighting off infections. This condition, known as neutropenia, compromises the immune response, making patients more vulnerable to infections.

Since chemotherapy affects hematopoietic cells and can lead to all these consequences, the correct answer is that all of the mentioned effects are commonly seen in patients undergoing such treatment.

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